reposting: The Dysautonomia Company
DISCLAIMER: this might now work for ALL forms of hyperhidrosis. But for the majority CHANCES ARE HIGH.
DYSAUTONOMIA is a condition caused by genetic mutations and is the ROOT CAUSE of a LARGE part of ALL primary HYPERHIDROSIS.
If your hyperhidrosis comes with any of the following: anxiety, digestive issues, insomnia, POTS, etc. then it is VERY likely that your underlying condition is Dysautonomia.
Some forms of hyperhidrosis MIGHT NOT come from Dysautonomia.
However, the majority DOES and for those that do:
There are solutions, that are non-obvious, but that are precisely effective.
Hello everyone,
I'm Alex, a dysautonomia & hyperhidrosis patient, and biotech entrepreneur.
For the past few months I have been working with the 2 leading researchers in the field of Dysautonomia and Hyperhidrosis ; most of their research is unpublished yet.
Today, we’re excited to introduce a new initiative dedicated to tackling dysautonomia and hyperhidrosis at their root cause.
Our mission is to bring real, science-backed solutions to people suffering from these conditions—solutions that address not just the symptoms, but also the underlying mechanisms driving them.
We are a team of scientists and entrepreneurs, advised by:
- Dr. Malcolm Brock, co-founder, a clinician and researcher from Johns Hopkins, who has treated countless patients with dysautonomia and hyperhidrosis.
- Dr. Frank Bosmans, co-founder a leading researcher in electrophysiology, specializing among other topics, in the role of ion channels in nervous system function.
Through years of clinical experience and research, they’ve uncovered critical insights that could revolutionize the way dysautonomia and hyperhidrosis are managed:
They have identified that these conditions are often linked to genetic mutations in ion channels, specifically Sodium, Calcium and/or Potassium channels.
These mutations cause the sympathetic nervous system to become hyperexcitable, leading to an overactive stress response. In dysautonomia, this results in symptoms such as shortness of breath, anxiety, insomnia, and poor digestion, while in hyperhidrosis, it triggers excessive sweating, particularly in the hands and feet.
The mechanism behind this dysfunction lies in the altered electrical signaling of nerve cells, where the faulty ion channels fail to properly regulate nerve excitability. As a result, the body remains in a heightened state of sympathetic dominance, contributing to chronic stress-related symptoms and discomfort.
Our approach focuses on three key stages, each aimed at providing relief while working toward a long-term solution:
1. Symptom-Targeted Supplementation
We are developing a supplement specifically designed to help manage dysautonomia symptoms by optimizing hydration, nerve function, and overall physiological balance. Our formula includes Electrolytes and specifically-tailored Amino Acids, as well as a few precise Vitamins & minerals, shown to work together to adress the symptoms of Dysautonomia and Hyperhidrosis.
This formulation is based on our research into electrolyte balance, neurotransmitter support, and metabolic optimization to help combat symptoms like dizziness, fatigue, and blood pressure fluctuations.
In Full transparency, here is the formulation of the supplement:
Sodium (Salt) - 1000 mg of Sodium (2-3 g of salt) for fluid retention.
Potassium Citrate - 1-2g fluid equilibrium
Magnesium Glycinate - 400 mg of elemental magnesium (3g of Mag Glycinate) - Nervous system calming effect.
Glucose, 10 grams, to facilitate electrolytes assimilation via glucose transporters.
Glycine, 5 grams. Calming amino acids, body temperature regulation.
Taurine, 5 grams regulates nervous system activity.
Zinc picolinate, 30 mg, regulates nerves membrane potential.
Vitamins Bs (100% daily value of B1, B3, B6 and B12), key for nerve membrane stabilization among other things.
Lion's mane, ion channel modulator and nervous system adaptogen.
CBDV 100-800mg. Cannabidivarin is different from CBD, it specifically targets the nervous system to reduce the hyperexcitability that is the cause of most forms of hyperhidrosis/dysautonomia.
Can be combined with full spectrum CBD oil. (make sure it's THC-free or low THC if you can't stand THC)
All of these ingredients play an important role and I will explain the more detailed scientific rational in my next posts.
Please try this combination everyday at 6pm for at least a month.
Ideally have all the first ingredients 1h before dinner and then the CBDV AFTER dinner to maximize absorption.
2. Repurposing Existing Medications
Our findings suggest that dysautonomia and hyperhidrosis are often caused by genetic mutations affecting ion channels (including Calcium, Sodium and Potassium channels), leading to an overactive sympathetic nervous system. We are actively working to repurpose off-patent medications that were found to work wonders for specific patients with specific mutations.
By bringing these treatments to market with a dysautonomia-specific focus, we hope to provide more effective and accessible options for patients.
3. Long-Term Vision: Gene Therapy & Diagnostics
Ultimately, we aim to build a genetic mutation database to enable precise diagnosis and treatment, with the goal of developing gene therapies that can address the root cause of dysautonomia at the molecular level. We believe that understanding the unique genetic profiles of individuals will pave the way for truly personalized medicine.
Why we do it: I know how frustrating and isolating it can be to live with dysautonomia and hyperhidrosis—conditions that are often misunderstood and misdiagnosed. Our goal is to provide real solutions based on science, empowering patients with tools to reclaim their lives and feel better.
This isn’t just another “miracle cure” or fad supplement; we are committed to transparency, clinical validation, and working closely with the dysautonomia community to ensure our solutions meet real needs.
We’d love to hear from you! Your experiences and feedback are invaluable as we refine our products and approach. If you’re interested in:
- Joining our early testing group
- Learning more about our medication research
- Staying updated on our progress
Drop a comment below, or DM me to get involved!
We’re looking forward to making a real impact together. Let’s bring hope and solutions to the dysautonomia and hyperhidrosis community.