What's the worst way you lost a run?

I've played for a little bit and I recently got to ante 6 and the boss blind was the needle. I had the DNA joker and by the time I was in the boss blind I forgot it was the needle. My monkey brain said, "copy your steel king," immediately realized my mistake as soon as I played the hand, and felt unbelievably dumb after. What's some of your stories of how you lost in silly/dumb ways?